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1

Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomised phase 2/3 trial

Al-Batran, Salah-Eddin, Hofheinz, Ralf D, Pauligk, Claudia, Kopp, Hans-Georg, Haag, Georg Martin, Luley, Kim Barbara, Meiler, Johannes, Homann, Nils, Lorenzen, Sylvie, Schmalenberg, Harald, Probst, St

Journal:

The Lancet Oncology

Year:

2016

Language:

english

File:

PDF, 325 KB

english, 2016

2

Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial

Rödel, Claus, Graeven, Ullrich, Fietkau, Rainer, Hohenberger, Werner, Hothorn, Torsten, Arnold, Dirk, Hofheinz, Ralf-Dieter, Ghadimi, Michael, Wolff, Hendrik A, Lang-Welzenbach, Marga, Raab, Hans-Rudo

Journal:

The Lancet Oncology

Year:

2015

Language:

english

File:

PDF, 490 KB

english, 2015

3

Gesundheitspädagogik statt Tröstung Die theologische Bewältigung von Krankheit bei Philipp Melanchthon und Caspar Peucer

Ralf Bröer and Ralf Hofheinz

Journal:

Sudhoffs Archiv

Year:

2001

File:

PDF, 3.05 MB

2001

4

Liposomal encapsulated anti-cancer drugs

Hofheinz, Ralf-Dieter, Gnad-Vogt, Senta Ulrike, Beyer, Ulrich, Hochhaus, Andreas

Journal:

Anti-Cancer Drugs

Year:

2005

Language:

english

File:

PDF, 190 KB

english, 2005

5

Oxaliplatin-Induced Acute ST Segment Elevation Mimicking Myocardial Infarction: A Case Report

Weidner, Kathrin, Behnes, Michael, Haas, Jenny, Rusnak, Jonas, Fuerner, Paul, Kuska, Mathieu, Mukherji, Agnibh, Borggrefe, Martin, Hofheinz, Ralf-Dieter, Akin, Ibrahim

Journal:

Oncology Research and Treatment

Year:

2018

Language:

english

File:

PDF, 354 KB

english, 2018

6

Therapeutic drug monitoring (TDM) of 5-fluorouracil (5-FU): new preanalytic aspects

Mindt, Sonani, Aida, Sihem, Merx, Kirsten, Müller, Annette, Gutting, Tobias, Hedtke, Maren, Neumaier, Michael, Hofheinz, Ralf-Dieter

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2019

Language:

english

File:

PDF, 201 KB

english, 2019

7

HER2 testing in gastric cancer diagnosis: insights on variables influencing HER2-positivity from a large, multicenter, observational study in Germany

Baretton, Gustavo, Kreipe, Hans H., Schirmacher, Peter, Gaiser, Timo, Hofheinz, Ralf, Berghäuser, Karl-Heinz, Koch, Winfried, Künzel, Claudia, Morris, Stefanie, Rüschoff, Josef

Journal:

Virchows Archiv

Year:

2019

Language:

english

File:

PDF, 448 KB

english, 2019

8

Statement to an Insufficient Systematic Review on Viscum album L. Therapy

Matthes, Harald, Thronicke, Anja, Hofheinz, Ralf-Dieter, Baars, Erik, Martin, David, Huber, Roman, Breitkreuz, Thomas, Bar-Sela, Gil, Galun, Daniel, Schad, Friedemann

Journal:

Evidence-based Complementary and Alternative Medicine

Year:

2020

File:

PDF, 939 KB

2020

9

Phase I trial of cetuximab in combination with capecitabine, weekly irinotecan, and radiotherapy as neoadjuvant therapy for rectal cancer

Ralf-Dieter Hofheinz, Karoline Horisberger, Christoph Woernle, Frederik Wenz, Uta Kraus-Tiefenbacher, Georg Kähler, Dietmar Dinter, Rainer Grobholz, Steffen Heeger, Stefan Post, Andreas Hochhaus, Fran

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2006

Language:

english

File:

PDF, 128 KB

english, 2006

10

Oxaliplatin and Capecitabine-Based Chemoradiotherapy for Gastric Cancer—An Extended Phase I MARGIT and AIO Trial

Ralf-Dieter Hofheinz, Frederik Wenz, Nadine Lukan, Sabine Mai, Melanie Kripp, Wilko Staiger, Matthias Schwarzbach, Frank Willeke, Markus Möhler, Stefan Post, Andreas Hochhaus

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2009

Language:

english

File:

PDF, 148 KB

english, 2009

11

Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy

Juliana Schwaab, Karoline Horisberger, Philipp Ströbel, Beatrice Bohn, Deniz Gencer, Georg Kähler, Peter Kienle, Stefan Post, Frederik Wenz, Wolf-Karsten Hofmann, Ralf-Dieter Hofheinz, Philipp Erben

Journal:

Year:

2011

Language:

english

File:

PDF, 223 KB

english, 2011

12

A prospective, non-randomized phase II trial of Trastuzumab and Capecitabine in patients with HER2 expressing metastasized pancreatic cancer

Andre Mihaljevic, Peter Büchler, Jan Harder, Ralf Hofheinz, Michael Gregor, Stephan Kanzler, Wolff Schmiegel, Volker Heinemann, Esther Endlicher, Günter Klöppel, Thomas Seufferlein, Michael Geissler

Journal:

Year:

2009

Language:

english

File:

PDF, 528 KB

english, 2009

13

Induction Chemotherapy before Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer

Claus Rödel, Dirk Arnold, Heinz Becker, Rainer Fietkau, Michael Ghadimi, Ullrich Graeven, Clemens Hess, Ralf Hofheinz, Werner Hohenberger, Stefan Post, Rudolf Raab, Rolf Sauer, Frederick Wenz, Torsten

Journal:

Strahlentherapie und Onkologie

Year:

2010

Language:

english

File:

PDF, 292 KB

english, 2010

14

SevereChlamydia pneumoniaeinfection in a patient with mild neutropenia during treatment of Hodgkin’s disease

Margit Hummel, Ralf Hofheinz, Dieter Buchheidt

Journal:

Annals of Hematology

Year:

2004

Language:

english

File:

PDF, 129 KB

english, 2004

15

Two potential mechanisms of oxaliplatin-induced haemolytic anaemia in a single patient

Ralf-Dieter Hofheinz, Xuan-Duc Nguyen, Dieter Buchheidt, Mohammed Kerowgan, Rüdiger Hehlmann, Andreas Hochhaus

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2004

Language:

english

File:

PDF, 121 KB

english, 2004

16

Efficacy and safety of capecitabine in combination with docetaxel and mitomycin C in patients with pre-treated pancreatic, gallbladder, and bile duct carcinoma

Jens Kruth, Johanna Nissen, Thomas Ernst, Melanie Kripp, Nadine Lukan, Kirsten Merx, Wolf-Karsten Hofmann, Andreas Hochhaus, Ralf-Dieter Hofheinz

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2010

Language:

english

File:

PDF, 321 KB

english, 2010

17

First-line panitumumab plus irinotecan/5-fluorouracil/leucovorin treatment in patients with metastatic colorectal cancer

Claus-Henning Köhne, Ralf Hofheinz, Laurent Mineur, Henry Letocha, Richard Greil, Josef Thaler, Eva Fernebro, Erick Gamelin, Lucy DeCosta, Meinolf Karthaus

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 584 KB

english, 2012

18

Conditional reactive simulatability

Michael Backes, Markus Dürmuth, Dennis Hofheinz, Ralf Küsters

Journal:

International Journal of Information Security

Year:

2008

Language:

english

File:

PDF, 409 KB

english, 2008

19

Combined Adjuvant Radiochemotherapy With IMRT/XELOX Improves Outcome With Low Renal Toxicity in Gastric Cancer

Judit Boda-Heggemann, Ralf-Dieter Hofheinz, Christel Weiss, Philipp Mennemeyer, Sabine K. Mai, Petra Hermes, Hansjörg Wertz, Stefan Post, Bernd Massner, Udo Hieber, Andreas Hochhaus, Frederik Wenz, Fr

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2009

Language:

english

File:

PDF, 380 KB

english, 2009

20

Detection of centrosome aberrations in disease-unrelated cells from patients with tumor treated with tyrosine kinase inhibitors

Michelle Giehl, Armin Leitner, Claudia Haferlach, Peter Duesberg, Wolf-Karsten Hofmann, Ralf Hofheinz, Wolfgang Seifarth, Andreas Hochhaus, Alice Fabarius

Journal:

European Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 293 KB

english, 2010

21

Comparison of [18F]FDG uptake and distribution with hypoxia and proliferation in FaDu human squamous cell carcinoma (hSCC) xenografts after single dose irradiation

Bruechner, Kerstin, Bergmann, Ralf, Santiago, Alina, Mosch, Birgit, Yaromina, Ala, Hessel, Franziska, Hofheinz, Frank, van den Hoff, Joerg, Baumann, Michael, Beuthien-Baumann, Bettina

Journal:

International Journal of Radiation Biology

Year:

2009

Language:

english

File:

PDF, 981 KB

english, 2009

22

Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial

Ralf-Dieter Hofheinz, Frederik Wenz, Stefan Post, Axel Matzdorff, Stephan Laechelt, Jörg T Hartmann, Lothar Müller, Hartmut Link, Markus Moehler, Erika Kettner, Elisabeth Fritz, Udo Hieber, Hans Walte

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 352 KB

english, 2012

23

KRAS and BRAF Mutations and PTEN Expression Do Not Predict Efficacy of Cetuximab-Based Chemoradiotherapy in Locally Advanced Rectal Cancer

Philipp Erben, Philipp Ströbel, Karoline Horisberger, Juliana Popa, Beatrice Bohn, Benjamin Hanfstein, Georg Kähler, Peter Kienle, Stefan Post, Frederik Wenz, Andreas Hochhaus, Ralf-Dieter Hofheinz

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2011

Language:

english

File:

PDF, 140 KB

english, 2011

24

Phase II study of plitidepsin in pretreated patients with locally advanced or metastatic non-small cell lung cancer

Peschel, Christian, Hartmann, Joerg T., Schmittel, Alexander, Bokemeyer, Carsten, Schneller, Folker, Keilholz, Ulrich, Buchheidt, Dieter, Millan, Susana, Izquierdo, Miguel Ángel, Hofheinz, Ralf-Dieter

Journal:

Year:

2008

Language:

english

File:

PDF, 144 KB

english, 2008

25

Pan-Histone Deacetylase Inhibitor Panobinostat Sensitizes Gastric Cancer Cells to Anthracyclines via Induction of CITED2

Ivonne Regel, Lisa Merkl, Teresa Friedrich, Elke Burgermeister, Wolfgang Zimmermann, Henrik Einwächter, Ken Herrmann, Rupert Langer, Christoph Röcken, Ralf Hofheinz, Roland Schmid, Matthias P. Ebert

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 7.23 MB

english, 2012

26

Skin toxicity and quality of life in patients with metastatic colorectal cancer during first-line panitumumab plus FOLFIRI treatment in a single-arm phase II study

Josef Thaler, Meinolf Karthaus, Laurent Mineur, Richard Greil, Henry Letocha, Ralf Hofheinz, Eva Fernebro, Erick Gamelin, Ana Baños, Claus-Henning Köhne

Journal:

Year:

2012

Language:

english

File:

PDF, 226 KB

english, 2012

27

Phase I study of imatinib, cisplatin and 5-fluoruracil or capecitabine in advanced esophageal and gastric adenocarcinoma

Martina Mayr, Karen Becker, Nadine Schulte, Sebastian Belle, Ralf Hofheinz, Annekatrin Krause, Roland M Schmid, Christoph Röcken, Matthias P Ebert

Journal:

Year:

2012

Language:

english

File:

PDF, 308 KB

english, 2012

28

Molecular Analysis of Desmoid Tumors with a High-Density Single-Nucleotide Polymorphism Array Identifies New Molecular Candidate Lesions

Erben, Philipp, Nowak, Daniel, Sauer, Christian, Ströbel, Philipp, Hofmann, Wolf-Karsten, Hofheinz, Ralf-Dieter, Hohenberger, Peter, Kasper, Bernd

Journal:

Year:

2012

Language:

english

File:

PDF, 477 KB

english, 2012

29

Cetuximab-Based Treatment of Metastatic Anal Cancer: Correlation of Response with KRAS Mutational Status

Lukan, Nadine, Ströbel, Philipp, Willer, Andreas, Kripp, Melanie, Dinter, Dietmar, Mai, Sabine, Hochhaus, Andreas, Hofheinz, Ralf-Dieter

Journal:

Year:

2009

Language:

english

File:

PDF, 217 KB

english, 2009

30

Annexin and Survivin in Locally Advanced Rectal Cancer: Indicators of Resistance to Preoperative Chemoradiotherapy?

Horisberger, Karoline, Erben, Philipp, Ströbel, Philipp, Bohn, Beatrice, Hahn, Melanie, Kähler, Georg, Wenz, Frederik, Hochhaus, Andreas, Post, Stefan, Willeke, Frank, Hofheinz, Ralf-Dieter

Journal:

Year:

2010

File:

PDF, 227 KB

2010

31

Novel conjugation and combination strategies of mitomycin C with special focus on the current patent literature

Beyer, Ulrich, Hofheinz, Ralf-Dieter

Journal:

Expert Opinion on Therapeutic Patents

Year:

2005

Language:

english

File:

PDF, 238 KB

english, 2005

32

Quality of life of older adult patients receiving docetaxel-based chemotherapy triplets for esophagogastric adenocarcinoma: a randomized study of the Arbeitsgemeinschaft Internistische Onkologie (AIO)

Kripp, Melanie, Al-Batran, Salah-Eddin, Rosowski, Johanna, Pauligk, Claudia, Homann, Nils, Hartmann, JÃ¶rg Thomas, Moehler, Markus, Hofheinz, Ralf-Dieter

Journal:

Year:

2014

Language:

english

File:

PDF, 255 KB

english, 2014

33

Cerebral blood flow quantification in the rat: a direct comparison of arterial spin labeling MRI with radioactive microsphere PET

Agnieszka Boś, Ralf Bergmann, Klaus Strobel, Frank Hofheinz…

Journal:

EJNMMI Research

Year:

2012

Language:

english

File:

PDF, 762 KB

english, 2012

34

Mitomycin C and capecitabine in pretreated patients with metastatic gastric cancer: a multicenter phase II study

Miranda, Manuel Barreto, Hartmann, Jörg Thomas, Al-Batran, Salah-Eddin, Kripp, Melanie, Gencer, Deniz, Hochhaus, Andreas, Hofheinz, Ralf-Dieter, Merx, Kirsten

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2014

Language:

english

File:

PDF, 231 KB

english, 2014

35

Preoperative chemo(radio)therapy versus primary surgery for gastroesophageal adenocarcinoma: Systematic review with meta-analysis combining individual patient and aggregate data

Ronellenfitsch, Ulrich, Schwarzbach, Matthias, Hofheinz, Ralf, Kienle, Peter, Kieser, Meinhard, Slanger, Tracy E., Burmeister, Bryan, Kelsen, David, Niedzwiecki, Donna, Schuhmacher, Christoph, Urba, S

Journal:

European Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 1.79 MB

english, 2013

36

Poorly Differentiated Small Cell Carcinoma of the Pancreas

Berkel, Simone, Hummel, Frank, Gaa, Jochen, Back, Walter, Hofheinz, Ralf, Queisser, Wolfgang, Singer, Manfred V., L&ouml, hr, Matthias

Journal:

Year:

2004

Language:

english

File:

PDF, 412 KB

english, 2004

37

Multiplex profiling of tumor-associated proteolytic activity in serum of colorectal cancer patients

Yepes, Diego, Costina, Victor, Pilz, Lothar R., Hofheinz, Ralf, Neumaier, Michael, Findeisen, Peter

Journal:

PROTEOMICS - Clinical Applications

Year:

2014

Language:

english

File:

PDF, 640 KB

english, 2014

38

Preoperative Staging of Rectal Tumors: Comparison of Endorectal Ultrasound, Hydro-CT, and High-Resolution Endorectal MRI

Dinter, Dietmar J., Hofheinz, Ralf-Dieter, Hartel, Mark, Kaehler, Georg F.A.B., Neff, Wolfgang, Diehl, Steffen J.

Journal:

Year:

2008

File:

PDF, 403 KB

2008

39

Dose-dependent changes in renal1H-/23Na MRI after adjuvant radiochemotherapy for gastric cancer

Haneder, Stefan, Budjan, Johannes Michael, Schoenberg, Stefan Oswald, Konstandin, Simon, Schad, Lothar Rudi, Hofheinz, Ralf Dieter, Gramlich, Veronika, Wenz, Frederik, Lohr, Frank, Boda-Heggemann, Jud

Journal:

Strahlentherapie und Onkologie

Year:

2015

Language:

english

File:

PDF, 577 KB

english, 2015

40

Acute small-bowel toxicity during neoadjuvant combined radiochemotherapy in locally advanced rectal cancer: determination of optimal dose-volume cut-off value predicting grade 2–3 diarrhoea

Reis, Tina, Khazzaka, Edwin, Welzel, Grit, Wenz, Frederik, Hofheinz, Ralf–Dieter, Mai, Sabine

Journal:

Radiation Oncology

Year:

2015

Language:

english

File:

PDF, 510 KB

english, 2015

41

Bevacizumab in first-line treatment of elderly patients with metastatic colorectal cancer: German community-based observational cohort study results

Hofheinz, Ralf, Petersen, Volker, Kindler, Manfred, Schulze, Mathias, Seraphin, Joerg, Hoeffkes, Heinz-Gert, Valdix, Anette-R, Schroeder, Jan, Herrenberger, Julia, Stein, Alexander, Hinke, Axel, Arnol

Journal:

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

42

Rectal cancer

Rödel, Claus, Hofheinz, Ralf, Liersch, Torsten

Journal:

Current Opinion in Oncology

Year:

2012

Language:

english

File:

PDF, 263 KB

english, 2012

43

Characteristics, Treatment and Prognostic Factors of Patients with Gynaecological Malignancies Treated in a Palliative Care Unit at a University Hospital

Aeckerle, Samantha, Moor, Marina, Pilz, Lothar R., Gencer, Deniz, Hofheinz, Ralf-Dieter, Hofmann, Wolf-Karsten, Buchheidt, Dieter

Journal:

Year:

2013

Language:

english

File:

PDF, 688 KB

english, 2013

44

Presentation, Treatment, and Analysis of Prognostic Factors of Terminally ill Patients with Gastrointestinal Tumors

Gencer, Deniz, K&auml, stle-Larralde, Nicola, Pilz, Lothar R., Weiss, Adelheid, Buchheidt, Dieter, Hochhaus, Andreas, Hofheinz, Ralf-Dieter

Journal:

Year:

2009

File:

PDF, 181 KB

2009

45

Cancer Patients and Advance Directives: A Survey of Patients in a Hematology and Oncology Outpatient Clinic

Hubert, Elisabeth, Schulte, Nadine, Belle, Sebastian, Gerhardt, Axel, Merx, Kirsten, Hofmann, Wolf-Karsten, Stein, Alexander, Burkholder, Iris, Hofheinz, Ralf-Dieter, Kripp, Melanie

Journal:

Year:

2013

File:

PDF, 287 KB

2013

46

Ramucirumab as second-line treatment for patients with metastatic esophagogastric adenocarcinoma

Hofheinz, Ralf-Dieter, Lorenzen, Sylvie

Journal:

Expert Review of Anticancer Therapy

Year:

2015

Language:

english

File:

PDF, 241 KB

english, 2015

47

Docetaxel, oxaliplatin and capecitabine (TEX regimen) in patients with metastatic gastric or gastro-esophageal cancer: Results of a multicenter phase I/II study

Stein, Alexander, Arnold, Dirk, Thuss-Patience, Peter C., Moehler, Markus, Grothe, Wilfried, Seufferlein, Thomas, Reinacher-Schick, Anke, Geissler, Michael, Hofheinz, Ralf-Dieter, Schmoll, Hans-Joachi

Journal:

Acta Oncologica

Year:

2014

Language:

english

File:

PDF, 124 KB

english, 2014

48

Adjuvant chemotherapy for rectal cancer

Hofheinz, Ralf-Dieter, Rödel, Claus, Burkholder, Iris, Kienle, Peter

Journal:

The Lancet Oncology

Year:

2015

Language:

english

File:

PDF, 43 KB

english, 2015

49

Improving Patient Outcomes with Regorafenib for Metastatic Colorectal Cancer - Patient Selection, Dosing, Patient Education, Prophylaxis, and Management of Adverse Events

Hofheinz, Ralf-Dieter, Arnold, Dirk, Kubicka, Stefan, Prasnikar, Nicole, Vogel, Arndt

Journal:

Oncology Research and Treatment

Year:

2015

Language:

english

File:

PDF, 193 KB

english, 2015

50

Workload and Quality of Life of Medical Doctors in the Field of Oncology in Germany - a Survey of the Working Group Quality of Life of the AIO for the Study Group of Internal Oncology

Hipp, Matthias, Pilz, Lothar, Al-Batran, Salah E., Hautmann, Matthias G., Hofheinz, Ralf-Dieter

Journal:

Oncology Research and Treatment

Year:

2015

Language:

english

File:

PDF, 186 KB

english, 2015